P-Shot (Priapus Shot) and Peyronie’s Disease


Peyronie’s disease is a curvature of the penis caused by scar tissue on one side of the penis. This condition can affect a man at any age.


The causes of Peyronie’s vary, yet are not always known. Trauma to the penis, which causes internal bleeding and scar (or plaque) formation is the most common cause; however, the trauma can be very mild and go unnoticed at the time. Other theories involve a genetic risk.


When the penis is erect, the hardened plaque will cause the penis to bend or curve. This curvature can cause pain and interfere with a man’s ability to have sexual intercourse.


Up until this point, there were very few effective treatment options for Peyronie’s Disease. Medications have been tried, both orally (Pentoxifylline) and injected directly into the plaque (Verapamil or Xiaflex), which do not tend to be very effective, and pose risk for penile fracture. A final option is surgery to remove the plaque or surgery to alter the tissue on the opposite side of the penis, called the Nesbit procedure. Side effects of these treatments include issues with erectile dysfunction and shortening of the penis.

We have two alternative treatment options which are free from the side effects from drugs or surgery.

The GAINSWave Procedure

The P-Shot® or Priapus Shot®. The P-Shot® utilizes PRP, or platelet rich plasma.


PRP, or platelet rich plasma, is a technology used in orthopedic surgery over the last decade to treat musculoskeletal injuries. Over 7,000 papers have been published speaking to the efficacy of PRP in healing tissue. A small amount of blood is drawn from the arm. Using a centrifuge, the we isolate platelets from your blood (platelet rich plasma, or PRP), all within about 15 minutes in the office. The platelets are then “activated” to release at least eight growth factors that would normally be used to heal injured tissue. These growth factors work like magic to cause increased collagen, blood flow, and break down the hardened plaque causing the curvature.

Added benefits of PRP in the form of the Priapus Shot® include:

  • Increased size of penis

  • Straightened penis

  • Increased circulation within the penis for a healthier organ

  • Additional therapies like Viagra® or Cialis® work better

  • Increased sensation and pleasure


P-Shot® for MEN $1,900 (Repeat, if needed at 12 weeks: $1,200) Procedure time: 1 hour

Dr. Rob Kominiarek of Renue Health is a licensed provider of the Regenerative Medicine procedures and The GAINSWave™ Procedure

*Results and patient experience may vary.

ReNue Health is located conveniently in Dayton, Ohio with easy access from Dayton International Airport, Cincinnati International Airport or the adjacent Wright Brothers Private Airport (MGY) for those travelling by private aviation.

Our office is open Monday through Friday, 9 am to 4:30 pm EST. You can reach us by phone at 937-350-5527 or send us an email through our directions and contact information page.

To learn how the ReNue Health Opportunity may help restore your youth and vitality, simply call